Honorlock is an online proctoring service that allows studen…

Honorlock is an online proctoring service that allows students to take exams remotely in an appropriate testing environment while ensuring that everyone in the course is representing their own learning, ideas, work, and current level of understanding with integrity.

Suppose a researcher studied the association between radiati…

Suppose a researcher studied the association between radiation exposure and prostate cancer among Floridian males aged 70+ using a retrospective cohort study. Suppose the researcher sampled 1.4% of Floridan males aged 70+ exposed to radiation and 3.6% of Floridian males aged 70+ not exposed to radiation. When it comes to prostate cancer, the researcher sampled 2% of Floridian males aged 70+ with prostate cancer, and 1% of Floridian males aged 70+ without prostate cancer.   Based on the information presented above, will there be selection bias in the estimate of the association between radiation exposure and prostate cancer (yes/no)? (2 points) Explain your answer (max. 8 points).

Case 2 (Questions 19 and 20) Suppose a team of researchers c…

Case 2 (Questions 19 and 20) Suppose a team of researchers conducted a prospective cohort study on the effect of physical activity on the 6-month risk of depression. To assess potential effect modification by gender, the researchers estimated the effect of physical activity on depression separately for men and women. In men, the estimated risk difference was -0.11 and the estimated risk ratio was 0.71. In women, the estimated risk difference was -0.07 and the estimated risk ratio was 0.80. Based on these effect estimates the researchers concluded that gender is indeed an effect modifier, so the researchers decided to report the conditional effect estimates in their manuscript. After submitting the manuscript for publication, a reviewer comments that gender may also be a confounder of the effect of physical activity on depression and that it would be important to adjust for gender in the analyses. The team of researchers from case 2 agrees with the reviewer that gender may be a confounder, however they argue that their conditional effect estimates are already adjusted for confounding by gender. Please describe how stratification addresses: Confounding by gender in case 2 (max. 3 points). Effect modification by gender in case 2 (max. 3 points).

Case 2 (Questions 19 and 20) Suppose a team of researchers c…

Case 2 (Questions 19 and 20) Suppose a team of researchers conducted a prospective cohort study on the effect of physical activity on the 6-month risk of depression. To assess potential effect modification by gender, the researchers estimated the effect of physical activity on depression separately for men and women. In men, the estimated risk difference was -0.11 and the estimated risk ratio was 0.71. In women, the estimated risk difference was -0.07 and the estimated risk ratio was 0.80. Based on these effect estimates the researchers concluded that gender is indeed an effect modifier, so the researchers decided to report the conditional effect estimates in their manuscript. After submitting the manuscript for publication, a reviewer comments that gender may also be a confounder of the effect of physical activity on depression and that it would be important to adjust for gender in the analyses. The team of researchers from case 2 agrees with the reviewer that gender may be a confounder, however they argue that their conditional effect estimates are already adjusted for confounding by gender. Please describe how stratification addresses: Confounding by gender in case 2 (max. 3 points). Effect modification by gender in case 2 (max. 3 points).