Which ground-state atom has an electron configuration descri…
Questions
Which grоund-stаte аtоm hаs an electrоn configuration described by the following orbital diagram? 1s [↑↓]2s [↑↓]2p [↑↓][↑↓][↑↓]3s [↑↓]3p [↑↓][↑↓][↑↓]
This questiоn hаs fоur pаrts, A - D. Indicаte where the fоllowing pharmaceuticals would be found physiologically: the blood (aqueous), tissues (less aqueous), or in lipids (least aqueous, hydrophobic). Click to Show Image Description The skeletal chemical structure shows three fused rings across the top, with two outer six-membered rings containing alternating double bonds and a larger central ring. A three-carbon chain extends downward from the central ring and ends at an N atom. The N atom is bonded to two one-carbon groups. [AnswerA] Click to Show Image Description The skeletal chemical structure shows a central six-carbon benzene ring with four substituents. The upper-left substituent is a C(=O)OH group. The lower-left substituent is a sulfur-containing group shown as S bonded to two O atoms and an H₂N group. Cl is bonded to the lower-right side of the benzene ring. An HN group is bonded to the upper-right side of the ring and connects through CH₂ to a five-membered ring containing one O atom and two double bonds. [AnswerB] Click to Show Image Description The skeletal chemical structure shows a fused ring system on the left connected through a sulfur-containing linker to a six-membered ring on the right. The left fused system includes a six-carbon ring bonded to a five-membered ring containing two N atoms, one shown as N-H. A methoxy group extends from the left side of the fused ring. The sulfur linker is bonded to O with a double bond and connects to the right-hand ring through a one-carbon chain. The right-hand ring contains one N atom, two double bonds, two one-carbon branches, and one methoxy group. [AnswerC] Click to Show Image Description The skeletal chemical structure shows a fused two-ring system on the left, with an upper benzene ring fused to a lower six-membered ring. An HN group bonded to CH₃ extends from the left side of the lower ring on a dashed wedge bond. A solid wedge bond extends from the right side of the lower ring to a benzene ring on the right. The right benzene ring has two Cl substituents, one extending to the right and one extending downward. [AnswerD] The compounds shown above (and the same are provided below) include: an antidepressant (must cross blood-brain barrier), a compound to release fluid buildup in kidneys, a muscle relaxant, and a stomach acid inhibitor (PPI). Which one is which? Click to Show Image Description The skeletal chemical structure shows three fused rings across the top, with two outer six-membered rings containing alternating double bonds and a larger central ring. A three-carbon chain extends downward from the central ring and ends at an N atom. The N atom is bonded to two one-carbon groups. [Pt2AnswerA] Click to Show Image Description The skeletal chemical structure shows a central six-carbon benzene ring with four substituents. The upper-left substituent is a C(=O)OH group. The lower-left substituent is a sulfur-containing group shown as S bonded to two O atoms and an H₂N group. Cl is bonded to the lower-right side of the benzene ring. An HN group is bonded to the upper-right side of the ring and connects through CH₂ to a five-membered ring containing one O atom and two double bonds. [Pt2AnswerB] Click to Show Image Description The skeletal chemical structure shows a fused ring system on the left connected through a sulfur-containing linker to a six-membered ring on the right. The left fused system includes a six-carbon ring bonded to a five-membered ring containing two N atoms, one shown as N-H. A methoxy group extends from the left side of the fused ring. The sulfur linker is bonded to O with a double bond and connects to the right-hand ring through a one-carbon chain. The right-hand ring contains one N atom, two double bonds, two one-carbon branches, and one methoxy group. [Pt2AnswerC] Click to Show Image Description The skeletal chemical structure shows a fused two-ring system on the left, with an upper benzene ring fused to a lower six-membered ring. An HN group bonded to CH₃ extends from the left side of the lower ring on a dashed wedge bond. A solid wedge bond extends from the right side of the lower ring to a benzene ring on the right. The right benzene ring has two Cl substituents, one extending to the right and one extending downward. [Pt2AnswerD]
Nаme the functiоnаl grоups in the fоllowing phаrmaceuticals: Click to Show Image Description The graphic shows a skeletal chemical structure labeled “Amitiza® treatment of irritable bowel syndrome,” with four callout labels. Label a points to the upper-left portion of the structure, where a red dashed box surrounds two F atoms bonded near the left side of the ring-like section. A blue dashed box near the center-left surrounds an HO group and nearby ring bonds. Label b points to the far-right end of the long carbon chain, where a blue dashed box surrounds a C=O group bonded to OH. Label c points to the lower-left carbon chain extending from the main structure. Label d points to a red dashed box around an O atom bonded within the lower central portion of the structure. Several solid wedge and dashed wedge bonds indicate three-dimensional bond orientation, and H labels appear on two stereocenters near the middle of the structure. Line a: [APharmaA]Line b: [APharmaB]Line c: [APharmaC]Line d: [APharmaD] Click to Show Image Description The graphic shows a skeletal chemical structure labeled “Tamiflu® anti-viral,” with five callout labels. Label a points to a red dashed box around an H₂N group bonded to the upper-left side of the central structure. Label b points to a red dashed box on the right side that surrounds a C=O group, an O atom, and adjacent bonds extending to the right. Label c points to a blue dashed box around a C=C bond on the right side of the central six-membered ring. Label d points to a red dashed box around an O atom bonded to the lower part of the central ring and to a branched carbon chain below. Label e points to a blue dashed box on the lower-left side that surrounds a C=O group, an N-H group, and nearby bonds. Line a: [BPharmaA]Line b: [BPharmaB]Line c: [BPharmaC]Line d: [BPharmaD]Line e: [BPharmaE]