Using the letters corresponding to the stages in the physiol…
Questions
Using the letters cоrrespоnding tо the stаges in the physiology of muscle contrаction, write the events of muscle contrаction in chronological order in the space provided. Note: The first step begins somewhere in the neuron as I want to determine if you still understand some of the steps that take place in the neuron from previous notes. a. Action potentials are conducted in a motor neuron and arrive at the terminal of the axon. b. Action potentials stop being produced, SR accumulates calcium and the troponin-tropomyosin complex moves again to its inhibitory position. c. ACh diffuses across cleft and binds to ACh receptors. d. Action potentials are conducted across the muscle cell membrane (sarcolemma). e. Shape change in troponin causes tropomyosin to shift position in the actin filament, thus exposing binding sites for the myosin cross-bridges. f. Attachment of another ATP allows the cross bridge to detach from the actin and repeat the cycle over again as long as Ca2+ remains attached to troponin. g. Binding of ACh to receptors opens up ion channels on muscle cell membrane that causes EPP’s and a depolarization of the muscle. h. Myosin cross-bridges bind ATP, attach to actin, and undergo a power stroke. i. Voltage-gated Ca2+ channels open in pre-synaptic terminal and Ca2+ enters cell. j. Ca2+ attaches to troponin, causing a conformational change in its structure. k. T tubules conduct action potentials deep into the muscle fiber. l. Ca2+ entry causes the release of ACh at the neuromuscular junction. m. Action potentials in the T tubule stimulate the release of Ca2+ from the terminal cisternae.