Today’s episode of Democracy Now! is all about the genetics…
Questions
Tоdаy's episоde оf Democrаcy Now! is аll about the genetics of sickle cell anemia or sickle cell disease (SCD). More than 100 million people are carriers of the sickle cell trait throughout the world, and millions of people live with SCD. SCD is most common in Africa, the Middle East, and India. The hosts of Democracy Now! have invited you to explain how the sickle cell trait is inherited and how the combination of one sickle cell allele (s) and one normal hemoglobin allele (A) protects people from malaria. During the episode, one of the hosts asks you to explain this specific case: Kemi and Tunde are very excited to have a family with four children. Tunde knows that he's a carrier but does not have SCD. Kemi isn't sure about her chances of having children with SCD. While Kemi's father has SCD, her mother does not have SCD and is not a carrier of the sickle cell allele. Hint: Use a Punnett square to determine the expected genotype percentages for each pregnancy. When creating your Punnett square, use "s" to represent the sickle cell allele and "A" to represent the allele for normal hemoglobin. What is the genotype of Kemi's mother? What is the genotype of Kemi's father? (4 points) What genotypes would Kemi's parents be expected to produce in their children? Please include the percentage for each genotype. (4 points) What are the possible genotypes of the children of Kemi and Tunde? What percentage of their children would be expected to have each genotype? (4 points) What are the possible phenotypes of Kemi and Tunde's children? What percentage of their children would be expected to have each phenotype? (4 points) Based on your Punnett square, what percentage of Kemi and Tunde's children would be expected to have SCD? What percentage of their children would have resistance to malaria? Please explain your reasoning. (4 points) Academic Integrity Please review my page on academic integrity in the opening module and my video on the homepage.