The SGLT (Sodium Glucose Transporter) requires the binding o…
Questions
The SGLT (Sоdium Glucоse Trаnspоrter) requires the binding of а sodium ion to а transmembrane protein on the external face of the ECF. With a sodium ion bound to the transporter, it will then bind a molecule of glucose. The binding of glucose then triggers a conformational change of the protein such that it opens to the ICF and releases the sodium and the glucose. The binding of sodium to this transporter is dependent on maintaining a higher concentration of sodium in the ECF relative to the ICF. The basolateral Na/K ATPase pump ensures that the intracellular concentration for sodium remains low which keeps the SGLT working. The energy for the transport of glucose provided indirectly by ATP hydrolysis. Match the key events of this scenario.