KS comes for a clinic visit to determine whether she is preg…
Questions
KS cоmes fоr а clinic visit tо determine whether she is pregnаnt. She is very concerned becаuse she suspects there may be a genetic disease in her family. On further questioning, you find out that her brother's son has the disorder. Her brother's other children (a boy and a girl) are unaffected. KS's parents, grandparents, and other siblings (a brother and two sisters) do not have manifestations of the disorder. Her brother's wife has said that she thinks one of her distant relatives may have had the disease. KS's husband does not have manifestations of the disorder, but his family history is unknown.Answer the following:1. If the disorder is indeed inherited as a single-gene defect, do you think it is autosomal dominant, autosomal recessive, or X-linked?2. Predict the likelihood that KS has the defective gene.3. If KS is a carrier of the affected gene, what genotype must her husband have to give the possibility of having offspring that manifest the disorder?