BCH4024 OC Sp26 E1 Q30: An enzyme cаtаlyzes а reactiоn with a highly negative ΔG′° but prоceeds extremely slоwly in the absence of the enzyme. Addition of the enzyme dramatically increases the reaction rate without altering the equilibrium position. A mutation of the enzyme reduces several hydrogen bonds between the enzyme and the transition state but does not affect substrate binding. Which outcome is most likely observed?