In a 1929 paper defining physiological homeostasis, Walter Cannon stated the four postulates below. Some systems of the body are under antagonistic control. The nervous system has a role in preserving the fitness of the internal environment. One chemical signal can have different effects in different tissues. Some systems of the body are under tonic control. Choose to answer only one of the following questions. Which postulate applies most closely to the concept that multiple receptors exist for a given ligand? Explain your answer using examples as needed. Which postulate applies most closely to the effects of glucagon and insulin? Explain your answer using examples as needed.
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