Category: Uncategorized

Long-term potentiation depends on insertion of NMDA receptors into the postsynaptic membrane

Why might estrogen partially improve ADHD symptoms in females during the follicular phase of the menstrual cycle?

What is the difference between constitutive and inducible transcriptional control, and which one is most relevant to synaptic plasticity?

Children with ADHD have a higher frequency of the VAL158 variant of the COMT gene compared to the MET158 variant. What is the functional consequence of this?

CD68 puncta within Iba1+ microglial soma increased after novelty exposure in the CA1 SR but not in the CA3 SR or in the gentle handling group. What does this finding indicate about the microglia?

What is the main role of CREB?

What determines whether Ca++ entry through NMDA receptors leads to LTP versus LTD?

Contextual fear conditioning increases H3 acetylation at the c-fos and BDNF promoters in the hippocampus, and this acetylation disappears after extinction. What does this tell us about epigenetic marks in neurons?

Which cytoskeletal component serves as the main “track” for long distance axonal transport?

Fragile X syndrome (FMR1 loss) and Tuberous Sclerosis (TSC1/2 loss) are both single-gene disorders associated with ASD, yet they affect different molecular pathways. What do they share in common at the synaptic level?