Category: Uncategorized

A 35-year-old patient is undergoing a routine complete blood count (CBC) as part of a follow-up for a known metabolic disorder. The patient reports no current symptoms such as fever or infection. Physical examination is unremarkable.Laboratory Findings:WBC count: 8.5 × 10³/µL (Reference: 4.5–11.0 × 10³/µL)Differential: Normal distribution of neutrophils, lymphocytes, and monocytesPeripheral smear: Large, dark-staining granules present in neutrophils, lymphocytes, and monocytes; granules resemble toxic granulation but are coarse and uniformly distributedPlatelet count: NormalRBC morphology: NormalClinical history: Patient has Hurler syndrome (a mucopolysaccharidosis)Which condition best explains these findings?

Micromegakaryocytes may be present in patients with PMF.

Which combination of surface markers is characteristic of myeloid stem cells and myeloblasts?

What platelet count is considered a sustained thrombocytosis according to WHO criteria for diagnosing ET?

What feature distinguishes B cell from T cell Acute Lymphoblastic Leukemia in terms of clinical presentation?

PV manifests with panmyelosis in the BM with increases in erythrocytes, granulocytes, and platelets.

An oncology patient has the results shown in this table:testday 1day 3WBC8.0 × 10³/µL (8.0 × 10⁹/L)2.0 × 10³/µL (2.0 × 10⁹/L)RBC3.50 × 10⁶/µL (3.50 × 10¹²/L)3.45 × 10⁶/µL (3.45 × 10¹²/L)HGB10.0 g/dL (100 g/L)9.9 g/dL (99 g/L)HCT29.8%29.5%PLT180 × 10³/µL (180 × 10⁹/L)150 × 10³/µL (150 × 10⁹/L)The most probable explanation is:

Match the following morphologic abnormalities seen in MDS with their descriptors.

What is the final stage of cell division (mitosis) in neutrophil development?

Two mutually exclusive projects have the following projected cash flows:   Year CF Project A CF Project B    0 -$50,000 -$50,000    1 15,625 0    2 15,625 0    3 15,625 0    4 15,625 0    5 15,625 99,500 If the required rate of return on these projects is 10%, which would be chosen and why?