Category: Uncategorized

A researcher identifies a putative enhancer of a kidney-specific gene. To test it for activity, they make four independent transgenic lines where this enhancer drives GFP using a minimal promoter. In three of the four transgenic lines, they observe only kidney-specific expression. In the fourth line, they observe both kidney expression as well as brain expression. Of the options below, which is the most logical explanation?

By beginning this exam, I acknowledge that I understand the expectations for academic integrity. I agree that I will complete this Examplify assessment without using unauthorized resources, without opening any external browsers, windows, or applications beyond Honorlock and Examplify, and without communicating with others in any way during the exam. I understand that Honorlock records my screen, webcam, and audio throughout the duration of the exam, and any suspicious behavior may be reviewed and reported according to Idaho State University’s academic integrity policies.

In what condition, an organization should consider using global purchasing?  Select “y” if the company should consider global purchasing; select “n” if the company should NOT.  ___[1]___ The domestic supplier is limited to capacity.  ___[2]___ Strikes happen every day in the offshore country.  ___[3]___ The offshore supplier can provide advanced technical services.  ___[4]___ The offshore country requested an unreasonable and extremely high tariff.  ___[5]___ The unit product price is lower in offshore countries.  ___[6]___ The offshore supplier is far from the organization and has a really long lead time. 

4. My sister isn’t short. She’s (pretty / tall / heavy).

Which position of the C-spine demonstrates the left intervertebral foramina with the CR 15-20 caudad? 

Identify the projection and position for this image: IMT 335 Final Exam # 100.png

Question 4: TGFB and Dynamic Reciprocity Part A: Transforming Growth Factor-beta (TGFB is a key signaling protein in the TME. Explain how TGFB is stored in the extracellular matrix and how it is maintained in a latent (inactive) state. Part B: Describe the specific “mechanical cue” mechanism that leads to the activation of TGFB from the ECM. Part C: Once activated, TGFB creates a positive feedback loop involving the ECM. Detail the steps of this loop and its end result on tissue composition.

The most commonly-used Cas9 requires a protospacer adjacent motif (PAM), typically NGG, near the target site to function.

Extra Credit [1 point] In this class, we learned about evidence-based practices, including how to analyze scientific evidence. We also learned about pseudotherapies, and how not evaluating the evidence carefully can lead clinicians to implement interventions that are not fully supported by the literature. This can ultimately affect our patients negatively.  Reflect on this process, and explain how you plan to incorporate what you learned in your future clinical practice. Provide an example to illustrate your reasoning (the example could be related to hearing intervention or any other area within the hearing and speech sciences). 

You are provided a large dataset of prior credit card transactions containing the transaction amount, location, purchase time and average daily balance for the customer along with a known outcome of whether the purchase was eventually deemed as fraudulent (Yes or No).  Your company would like you to create a machine learning model that would predict the probability of an incoming transaction as potentially fraudulent. If the model shows promise, then it would be used in a real-time system and would need to make its prediction in less than 1 second of processing time. You have a choice between creating a model using k-NN or using the Decision Tree algorithm.  Answer both questions: Which algorithm do you think would make the better choice? Why do you reach this conclusion?