Dolly was diagnosed was squamous cell carcinoma of the vagin…

Dolly was diagnosed was squamous cell carcinoma of the vaginal canal.  The cervix and entire vaginal canal are removed and submitted to the pathology gross room. At the bench the PA notes that the mass is 0.3cm from the distal resection margin, and 9.7cm from the proximal resection margin.  Based on these finds, which of the following structures could potential be involved by the pathology?

A 57-year-old woman noticed red pruritic lesion on her left…

A 57-year-old woman noticed red pruritic lesion on her left labium.  The biopsy shows large atypical cells lying singly or in small clusters within epidermis.  These cells are positive for cytokeratin and negative for melanoma markers.  What is the most likely diagnosis?

A 23-year-old, sexually active man has increasing number and…

A 23-year-old, sexually active man has increasing number and size of warty lesions slowly growing over the inner surface of the penile prepuce during the past year.  These lesions are excised, but 2 years later, similar lesions appear.  Which of the following conditions most likely predisposed him to development of these recurrent lesions?