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Which condition is characterized by the thickening of facial bones and enlarged phalanges due to excessive growth hormone in adulthood? 

Which of the following are characteristic clinical manifestations of Graves’ disease?

Describe the “permissive effect” that thyroid hormone has on growth hormone as discussed in the sources. Explain how a deficiency in thyroid hormone can lead to the clinical manifestations of cretinism.

Multiple Sclerosis is described as a Type IV hypersensitivity reaction. Detail the process by which cytotoxic T lymphocytes cause the demyelination of neurons. Furthermore, explain why the loss of these myelin sheets leads to the various motor and sensory dysfunctions observed in patients.

Which form of arthritis is specifically characterized by the deposition of uric acid crystals that can pierce and damage chondrocytes?

Which grade of sprain involves complete tearing of ligament?

Which condition is the leading cause of over 90% of all cerebrovascular accidents?

Which type of fracture occurs when broken segments of bone are forced inwards onto brain tissue, potentially increasing intracranial pressure?

Match the following spinal or joint conditions with their specific description or primary cause.

Which of the following are physical signs associated with Cushing Syndrome?