Prokaryotes usually have a single circular chromosome, while…

Prokaryotes usually have a single circular chromosome, while eukaryotic cells typically have multiple linear chromosomes.  (a) What types of problems does this create for eukaryotes (be specific)? (5 points) (b) How do eukaryotic cells deal with the problem of having linear ends on their chromosomes (be specific)? (5 points)

Let’s suppose you have isolated a mutant strain (called stra…

Let’s suppose you have isolated a mutant strain (called strain A) of E. coli in which the lac operon is not regulated properly. In this mutant strain, the lac operon is constitutively expressed in the absence of lactose (and glucose). To understand the nature of this defect, you create a merozygote in which the mutant strain contains an F’ factor with a normal lac operon and a normal lacI gene. You then compare the mutant strain and the merozygote with regard to their β-galactosidase activities in the presence and absence of lactose. (Note: glucose was not present in either case.) You obtain the following results: Strain Addition of lactose Amount (%) β-Galactosidase Normal (wild-type)  No