A patient presents with a recent history of weight gain, fatigue, loss of appetite, and complaints of very foamy urine. Physical exam notes the patient has developed peripheral edema. It is found upon routine testing that their Total Protein is 5.2 g/dL (Ref Range: 6.0-8.0 g/dL) and Albumin is 2.8 g/dL (Ref Range: 3.5-5.5 g/dL). Serum Protein Electrophoresis demonstrates: Result Reference Range Albumin 2.8 3.6-5.2 g/dL Alpha-1 0.1 0.2-0.5 g/dL Alpha-2 1.5 0.6-1.0 g/dL Beta 0.3 0.5-1.2 g/dL Gamma 0.5 0.7-1.6 g/dL Total Protein 5.2 6.0-8.0 g/dL Please answer the following: What is the most likely cause of this patient’s abnormal total protein and SPE results? How is the your answer for question 1 causing these results? Why does the patient have edema?
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