An RN working in a general medical-surgical unit is caring f…

An RN working in a general medical-surgical unit is caring for a 57-year-old female with a bladder infection. Two weeks prior to hospitalization, the patient was experiencing slight burning upon urination. She self-treated by increasing her intake of fluids, but her symptoms continued to worsen. One week later, she developed generalized abdominal pain and a fever. She presented to the hospital when the pain became unbearable and fever reached 104°F. She was admitted to the medical-surgical unit and started on multiple IV antibiotics with concern that she could be developing a kidney infection.  It is likely it is an E. coli infection.   Which line(s) of defense has/have been breached in this patient’s case?