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As a child, Brett was always bouncing off the walls at his parents’ social gatherings. As an adult, he’s energetic and often considered the life of the party. This is an example of _____________.

The immunological consequence of severe combined immunodeficiency disease (SCID) caused by a genetic defect in either RAG-1 or RAG-2 genes is:

In B cells, transport of immunoglobulin to the membrane is dependent on association with two invariant proteins, Igα and Igβ. Which of the following invariant proteins provide this function for the T-cell receptor in T cells? (select all that apply)

A genetic defect in the λ5 gene would cause which of the following consequences? (select all that apply)

Large pre-B cells are characterized by which of the following?

What is the fate of an immature B cell that encounters and has specificity for self antigen?

When expression of _______ is turned off in small pre-B cells, the result is the presence of P nucleotides but an absence of N nucleotides in around 50% of light-chain genes.

The complementarity-determining region (CDR) 1 and CDR2 loops of the T-cell receptor contact the _______.

Place the following phases of a B cell’s life history in the correct chronological order where 1 is the 1st step and 6 is the last: negative selection [a] attacking infection [b] finding infection [c] searching for infection [d] repertoire assembly [e] positive selection [f]

All of the following events occur within germinal centers except