A 29 year old male patient has a history of electrolytes imb…

A 29 year old male patient has a history of electrolytes imbalances, hypokalemia, and severe hypertension. This patient was found to have mutations in a gene encoding the epithelial sodium channel. Which of the following diseases is characteristic of this patient?

A woman of childbearing age presents with fever, joint pain,…

A woman of childbearing age presents with fever, joint pain, and a facial rash (see photo). Her urinalysis reveals hematuria and red blood cell casts. Which set of autoantibodies are most specific for her disorder and what is the most likely diagnosis on a renal biopsy?