Category: Uncategorized

Chronic antipsychotic use leads to receptor upregulation in the nigrostriatal pathway. This neuroadaptation is MOST associated with:

A patient on clozapine presents with fatigue and fever. His ANC returns at 900/µL. What is the MOST appropriate action?

A 7-year-old with ADHD has significant insomnia after starting methylphenidate ER. Which option is often used to target evening hyperarousal/insomnia related to ADHD?

A 40-year-old woman on risperidone 4 mg develops amenorrhea and galactorrhea. What is the MOST likely mechanism?

A patient starting buprenorphine asks why timing matters. Which property of buprenorphine explains the risk of precipitated withdrawal if started too early?

A patient with major depressive disorder has failed four antidepressant trials and augmentation with aripiprazole. Which next-line intervention reflects advanced, evidence-based care?

A 23-year-old uses nicotine daily and wants the most effective pharmacotherapy for smoking cessation. Which medication has strong evidence and is not a controlled substance?

A 34-year-old with opioid use disorder (OUD) requests medication treatment. He has used fentanyl daily and wants the option with the strongest evidence for reducing mortality. Which statement is MOST accurate about FDA-approved medications for OUD?

A 9-year-old boy meets DSM-5 criteria for ADHD, combined presentation. Symptoms are impairing at school and home despite behavioral interventions. No cardiac history and normal vitals. Which medication class is considered first-line for ADHD?

A patient with panic disorder starts an SSRI and reports increased jitteriness and anxiety in week 1. What is a common best practice to reduce this early activation?