A 34-year-old woman presents to office  with progressive wei…

A 34-year-old woman presents to office  with progressive weight gain over the past year. She reports increased fatigue, muscle weakness, and easy bruising. On physical examination, her blood pressure is elevated, and she has thinning skin  Her face appears round , and she has increased hair growth on her chin. Which of the following symptom combinations is most characteristic of Cushing’s disease?