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appears to be important for cancer cells becoming metastatic.

Nothing would change; this is the normal Ran-GAP and Ran-GEF distribution.

QUESTION 3 Zoë must acquire a business phone. She got the following mobile phone rates at Cell Zone. Answer the questions  that follow by referring to the table below:   Cell Zone’s two business options:   Name Cell Z Busy Ness Cell Z Bizniz Type Contract Pay per minute Fixed cost R100 None Free minutes 150 minutes None Cost per minute R1.20 R1.00           3.1 Write down a formula to work out the cost for Cell Z Busy Ness. (4) 3.2 Write down a formula to work out the cost for Cell Z Bizniz. (2) 3.3 Set up a table to compare the cost of the two options. Use the table below as a guide. (6)   Total min 0 100 200 300 400 500 Busy Ness             Bizniz               3.4  If Zoë on average phones 200 and 300 minutes a month, which one of the two options should she choose? (2)

continue to pump ions and to hydrolyze ATP, but only generate heat in the process.

have nothing to do with pH and reducing environment.

begin to pump Na+ in both directions.

peroxisome membrane proteins.

  QUESTION 2 Zoë decides she wants to start her own business. She has R30 000,00 in her savings account. She’s going to open a Cupcake shop in Sea Point selling special cupcakes. She first wants to set up a business plan before finally deciding whether to start the business. Below is a table Zoë set up with all her expenses.   Expenses Cost (R) Rent R4000 Electricity R850 Transport Train tickets – R300 monthly pass Ingredients R2100 for 300 cupcakes Unplanned R900   2.1 Make a list of Zoë’s fixed expenses. (3) 2.2 Make a list of Zoë’s variable expenses. (3) 2.3 If it costs Zoë R7,00 to make 1 cupcake calculate:      2.3.1 The selling price for 1 cupcake if its mark-up is 300%. Round your answer to the nearest rand.Use: Selling price = cost price + mark-up (3)   2.3.2 The profit she makes on one cupcake? (2) 2.4 Calculate the missing values for A to E in the table below.Use the following values: R6050,00 as the fixed expenditure amount.R7,00 as the cost price per cupcake.R28,00 as the income per cupcake. Cupcakes 0 100 200 300 400 500 600 Income R0 A R5600 R8400 B R14000 R16800 Expenses C R6750 D E R8850 R9550 R10250         (5) 2.5 Draw a graph of both the income and expenses on the same set of axis. (5) 2.6 Use your graph to answer the following questions.     2.6.1 Why does the expense line start at R6050,00? (2)   2.6.2 How many cupcakes should Zoë sell to make a profit? (3)   2.6.3 What is the cutting point called? Why is the point significant? (3)   2.6.4 For how many months will Zoë be able to support her business by paying for the fixed monthly expenses if she covers it with the money from her savings account? Use R30 000,00 as the amount in her savings account. (3) 2.7 Do you think it is a good idea for Zoë to open the business? Give a reason for your answer by taking the information from above into account (3)

Questions 1-5 Many amino acids in our diet are absorbed via the transcellular transport pathway by the intestinal epithelial cells. This process requires ATP hydrolysis by

replace Na+ binding with K+ binding.