7.  Matching.  Below are structures of biomolecules and coen…

7.  Matching.  Below are structures of biomolecules and coenzymes encountered in this course.  In the blank provided, write the number of the term that best describes/names the structure given.  (16 pts – 2 ea.)             a) _____                                                                                 b)  _____                                 c) _____                                                                                 d)  _____                                                                                                           e) _____                                                                                 f)  _____                                                                                                                    g) _____                                                                                 h)  _____                                           adenosine triphosphate                  8.  FAD                                        15.  S-adenosylmethionine alditol                                               9.  fructose                                  16.  sphingomyelin ascorbic acid                                  10.  glycerophospholipid                 17.  sucrose biotin                                              11.  lactose                                   18.  sugar phosphate carnitine                                         12.  lipoic acid                              19.  tetrahydrofolate coenzyme A                                   13.  NAD+                                     20.  thymine nucleotide cytidine nucleoside                       14.  oligopeptide                          21.  triacylglycerol

13.  Answer part a) or b), NOT both.      a) What will happe…

13.  Answer part a) or b), NOT both.      a) What will happen in a muscle cell if citrate is high?  Think about ALL pathways now – including fatty acid metabolism.  A successful answer will mention three key regulatory enzymes (2 ea.) and address at least four pathways (1 ea.) affected by this situation.  It has to be reasonable to receive full credit.  (10 pts)   OR      b)    Describe the events of the Q cycle of Complex III.  Begin with dihydroubiquinone binding the complex.  Be sure to account for two electrons going to Complex IV.  (10 pts)    

11.  A unicellular organism is discovered in remote lake. It…

11.  A unicellular organism is discovered in remote lake. It possesses no nucleus, haploid DNA, and an abundance of phosphatidylcholines in its cell membrane.      a) In which Domain does this organism belong:  Archaea, Bacteria, or Eukarya?  (2 pts)      b) The organism is found to be aerobic.  What does this mean?  (2 pts)      c) List the five characteristics of life, most of which this organism should exhibit.  (4 pts)      d) This organism’s F1F0-ATPase has 14 c subunits in its c collar.  Calculate the ATP yield from one of the following fuels – your choice.  Assume aerobic conditions and use of the malate-aspartate shuttle.  Do NOT do both.  (6 pts)                 myristic acid  (Myristic acid is 14:0.  Don’t forget the cost of activation.)         OR                          fructose-6-phosphate        e) The organism is found to biosynthesize glycine by the following novel pathway.  Below four of the yields arrows are blanks labeled 1 through 4; fill them in by either giving the specific enzyme class name or EC number of the enzyme employed.  For EC numbers, just fill in the given blanks; sometimes one or two digits are needed.  (6 pts – 1 ea. blank)         

12.  Below is the 5’ to 3’ sequence of DNA that codes for pa…

12.  Below is the 5’ to 3’ sequence of DNA that codes for part of a protein.          a) Use the given base sequence to construct both the mRNA sequence coded by the DNA and the protein coded by the mRNA.  You may use 1- or 3-letter code for the protein sequence.  You may construct the 3’ to 5’ DNA sequence from which the mRNA is built, but doing so is not necessary.  (6 pts – 3 pts mRNA; 3 pts protein) 5’ to 3’:  G A C C T A G C G C G T C T G G T G A G T C T C T T T G C T A T G T A T 3’ to 5’: mRNA: protein:         b) Examine the amino acid sequence you have found.  Does it code for an alpha-helix, beta-sheet, intrinsically disordered region, or loop?  Point out two features of the amino acid sequence that support your conclusion.  (6 pts)