The citric acid cycle begins with oxaloacetate accepting an…

The citric acid cycle begins with oxaloacetate accepting an acetyl group to form citrate. The two CO2 molecules removed during one turn of the cycle do not originate from the acetate incorporated during that turn. What is the best explanation why aconitase, the enzyme that acts on citrate, does not act on the acetyl-derived portion of this molecule? aconitase.png

Isocitrate dehydrogenase couples the oxidative decarboxylati…

Isocitrate dehydrogenase couples the oxidative decarboxylation of isocitrate to the reduction of NAD+ according to the two half-reactions i s o c i t r a t e → α – k e t o g l u t a r a t e + C O 2 + 2 e – + H + N A D + + H + + 2 e – → N A D H Select the free energy diagram that best describes the energetics of the enzyme-catalyzed electron transfer from isocitrate (iso) to NADH. ICDHcoupledRxn.png  

The isocitrate dehydrogenase-catalyzed citric acid cycle rea…

The isocitrate dehydrogenase-catalyzed citric acid cycle reaction isocitrate + NAD+ → α-ketoglutarate + CO2 + NADHwhere it’s  ∆Go’ = -8.4 kJ mol-1 , and given additional fee energy values in the Bx resource,Select the value in kJ mol-1 that is closest to the ∆Go’ for the uncatalyzed half-reactionisocitrate → α-ketoglutarate + CO2 + 2e-