A patient just back from Sierra Leone is admitted with high…

A patient just back from Sierra Leone is admitted with high fever and chills. His spleen is enlarged.  A giemsa stained blood smear shows intraerythrocytic  rings, some multiple with occasional “banana” shaped gametocytes.  This patient probably has:

The following substitution studies were performed on a patie…

The following substitution studies were performed on a patient’s plasma that had prolonged activated PTT.Patient plasma + normal plasmaFactor VIII,IX,XI deficient plasmas              None of the substitutions corrected the prolonged APTT significantly.  What could be the cause of these results?