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A 48-year-old patient reports a 6-month history of uncomfortable sensations in both legs occurring primarily in the evening. The patient describes an urge to move the legs that worsens at rest and improves temporarily with walking. Sleep has become fragmented as a result. Physical examination is normal. What is the most appropriate initial management step?

Which process most commonly leads to uncomplicated urinary tract infections in female patients?

A 59-year-old man reports erectile dysfunction and is taking sertraline for depression and a thiazide diuretic for hypertension. He asks what might be contributing. Which statement is most accurate?

A patient has an abnormality of kidney function lasting 6 weeks. They do not meet AKI (acute kidney injury) criteria but have an eGFR of 55 mL/min/1.73 m² with implications for health. Which classification best fits this presentation?

A 76-year-old man presents with decreased urine output and suprapubic fullness. Which etiology of acute kidney injury (AKI) is most likely?

A 28-year-old nonpregnant woman presents with fever (101.8°F), flank pain, nausea, and dysuria. Urinalysis shows pyuria and bacteriuria. The clinician plans outpatient treatment after giving an initial dose of ceftriaxone. Which oral antibiotic regimen is most appropriate for continued therapy?

A provider wants the preferred screening strategy for albuminuria in primary care. Which is best?

Which diagnostic test is recommended for screening chlamydia and gonorrhea?

A 64-year-old man presents with fever, dysuria, urinary frequency, and pelvic pain that began 3 days ago. He reports increasing difficulty urinating and generalized malaise. Physical examination reveals suprapubic tenderness and a markedly tender, boggy prostate on digital rectal examination. Which diagnostic finding would most strongly support the underlying cause of this patient’s symptoms?

A 74-year-old woman residing in a long-term care facility has a urine culture showing >100,000 CFU/mL of E. coli. She has no dysuria, fever, flank pain, or suprapubic discomfort. Vital signs are stable. What is the most appropriate management?