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CDR1 and CDR2, encoded by the V gene segment, recognize and primarily makes contact with the peptides loaded on the MHC.

Which of the following is false about Langerhans cells?

Signal transducers and activators of transcription (STATs) and janus kinases (JAK’s) are used in which signaling pathway/s?

What would be the result of a 35 year old male getting a thymectomy?

The pre-TCR complex is composed of a functional α chain, a surrogate β chain (preTβ), CD3 proteins and ζ chain.

Sphingosine 1-phosphate directs naive T-cells out of the lymph node back into the lymph.

Double negative thymocytes will simultaneously initiate rearrangement of which receptor genes first? 

Which of the following is false about positive selection?

Which of the following is false about TH2 cells?

Langerhans’ cells are a type of mature dendritic cells that take up antigens when the skin is breached.