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A 3-year-old male was admitted to a hospital with scattered petechiae and epitaxis. The patient had normal growth and had no other medical problems except for chicken pox 3 weeks earlier. His family history was unremarkable. Liver Function and Kidney Function tests are unremarkable.PT = 11.3 seconds (Ref: 10-13 secs)aPTT = 32.1 seconds (Ref: 28-37 secs)Plt Count = 8,000/uLThese clinical manifestations and laboratory results are most consistent with:

A patient has a platelet count of 80 × 109/L and a normal closure time. What is the most likely disorder?

Aliquots of plasma with a prolonged PT and prolonged aPTT are mixed using various ratios of patient plasma and normal plasma. All samples are incubated at 37oC and tested at 10-, 30-, and 60-minute intervals. The PT and aPTT results on all of the mixtures are corrected to normal limits. These results are suggestive of:

Which hemostatic disorder usually is represented by a decreased platelet count, normal PT, normal APTT, and abnormal PFA closure time?

Which of the following is not a mechanism of inducing thrombocytopenia in a patient?

51. Japan is currently the world’s leading “super-aged” society. Regarding the elderly in Japan, which of these theoretical statements is FALSE?

Splenomegaly can cause thrombocytopenia by which of the following mechanisms?

Patient presents with oozing 48 hours post tooth extraction. Results are as follows:PT: 11.5 seconds (Ref: 10-13 seconds)aPTT: 32.5 seconds (Ref: 23-35 seconds)Fibrinogen: 345 mg/dL (Ref: 200-400 mg/dL)Platelets: 324 x 103/uLThe most likely deficiency is:

A patient’s peripheral blood smear reveals many giant platelets. All platelet function tests show normal aggregation with the exception of ristocetin. From what is the patient most likely suffering?

A patient visits a physician because of unexplained bruising and prolonged bleeding from a recent tooth extraction. The physician orders a prothrombin time (PT) and an APTT. Results are within normal reference ranges. What other tests could the physician order to investigate the patient’s symptoms?