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Which of the following statements best describes the role of methadone in the treatment of opioid use disorder (OUD)? 

Methadone is classified by the Drug Enforcement Agency as a: 

A patient on an SGLT2 inhibitor presents with nausea, abdominal pain, and normal blood glucose (130 mg/dL), but elevated ketones. What is the most likely diagnosis?

A patient with type 2 diabetes is started on a once-daily insulin to provide steady glucose control throughout the day with minimal peaks. Which insulin is most appropriate?  

A patient with depression and a history of bulimia nervosa is being considered for pharmacotherapy.Which medication should be avoided?

TR is a 33 yo male currently receiving Morphine 30mg IV every 4 hours for pain post-operatively. He has developed severe pruritus and the NP has decided to switch to Hydromorphone. The conversion ratio for morphine to hydromorphone is 10:1.5. What would the correct dose of hydromorphone be? 

A patient is started on lithium for bipolar disorder. Which laboratory value is most important to monitor regularly? (Select all that apply)

A 68-year-old male with type 2 diabetes is treated with glipizide. He presents with diaphoresis and confusion after skipping a meal. What is the primary mechanism responsible for this adverse effect?    

A 32-year-old female patient presents to the clinic with a 6-month history of excessive worry about various aspects of her life, including work performance, health, and family issues. She reports that these worries are difficult to control and are associated with restlessness, fatigue, difficulty concentrating, irritability, muscle tension, and sleep disturbance. She has no past medical history of psychiatric disorders and does not use tobacco, alcohol, or illicit drugs. Her physical examination and laboratory tests are unremarkable. After a thorough evaluation, you diagnose her with generalized anxiety disorder (GAD) and decide to initiate pharmacotherapy. Which of the following would be considered first-line treatment for GAD? 

A 19-year-old patient is started on fluoxetine for major depressive disorder. At a 2-week follow-up, the patient reports increased agitation and new thoughts of self-harm. What is the most appropriate next step?