Blog

The mastoid tip is found on the _____ bone. 

All of the following are routine projections of the facial bones except: 

Match the following secondary messengers to their actions. 

 It is known that the amino acid at position 523 of the cyclooxygenase enzyme is part of the active site. In the isoenzyme COX-1, this amino acid is isoleucine, whereas in COX-2, it is valine. How such information could be used by a medicinal chemist to design of drugs that selectively inhibit COX-2?  This is important for nonsteroidal anti-inflammatory drugs that have no GI side effects.

The pre-clinical graph shown below appears reasonable. What is the name given to the ratio of TD50 to ED50?    

Which of the following inhibits adenylate cyclase? 

Identify which of the following terms refers to the subunit-subunit association of a protein.

The drug shown below is Prozac.  What type of drug is it?  

Isoprenaline is an adrenergic agonist. The isoprenaline analog shown below demonstrates a dramatic increase in activity in in vitro studies. What is the most likely conclusion that can be drawn?   

Which of the following is an enzyme involved in catalyzing Phase II metabolic reactions?