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A study is being designed to assess use of pre-exposure prophylaxis in men who have sex with men. The researchers decide to first recruit 5 eligible participants, and to then have these 5 participants help recruit other potentially eligible individuals from their social circles. The researchers give each of the first 5 eligible participants numbered coupons to hand out to other potentially eligible individuals, and use these coupons to track how each participant was recruited. Models are then built of the recruitment networks (based on coupons returned to researchers), and these models are used to estimate biases related to network density and homophily. This scenario best describes a __________ approach.

The Belmont Report principle of _________ requires that researchers obtain informed consent from all research participants.

The fact that certain types of people agree to participate in clinical trials may affect which of the following:

Which of the following is not a good reason for implementing a pilot study prior to the conduct of a randomized controlled trial?

Many popular news stories have covered the “replicability crisis” in science, noting how many research studies describe effects that cannot be later reproduced by other research teams. Initially focused largely on social psychology and related social science fields, this issue has now spread across the fields of medicine and public health. Which of the following practices is least likely to contribute to this problem?

Phenomenology is primarily focused on which of the following?

Which of the following biases are most affected by study recruitment protocols that employ nonprobability methods?

Of the following observational designs, which is the best for studying very rare health conditions?

Why is randomization used in “true” experiments?

Scientific rigor must be balanced by careful adherence to a code of research ethics. This includes respect for the word “no” when someone is asked to be in a study. In this regard, which concern (shown below) is the most likely aspect of rigor that may be sacrificed to protect ethics in research?