Membrane fusion between a vesicle and the plasma membrane is…

Membrane fusion between a vesicle and the plasma membrane is mediated by vSNARE/tSNARE binding. TRUE or FALSE:  This involves a stage in which a temporary lipid bilayer is formed between the original leaflet closest to the vesicle lumen and the original leaflet closest to the extracellular space (the area outside of the cell). 

A mouse line in Dr. Tolentino’s laboratory has acquired a no…

A mouse line in Dr. Tolentino’s laboratory has acquired a novel mutation impacting receptor-mediated endocytosis. When Dr. Tolentino examines the mouse cells under a microscope, she observes that coated pits and coated vesicles are forming, but they are accumulating at the plasma membrane and none are appearing in the cell cytosol, suggesting they they are not pinching off the cell surface.  What protein do you suspect the novel mutation has occurred in?