You are examining a term female neonate who was born after a…

You are examining a term female neonate who was born after an uneventful pregnancy to a 31 year old, gravida 2 para 1 mother by normal spontaneous vaginal delivery. On examination, the infant weighs 2.56kg and has mild diffuse hypotonia. He also has slightly short fingers and toes, simian creases, flat facial profile, upslanting palpebral fissures, and small ears. Of the following, the most likely diagnosis is:

Two weeks after undergoing surgical closure of an atrial sep…

Two weeks after undergoing surgical closure of an atrial septal defect, a 2 year old male presents with several days of irritability and anorexia. On physical exam, he is pale and mildly tachypneic. His pulses are weak and irregular. The auscultated heart rate is regular at 160 bpm. The most likely diagnosis is:

A 16-year-old boy is referred to with a history of malaise a…

A 16-year-old boy is referred to with a history of malaise and fatigue. He has not been sleeping well and complains of cough and nighttime sweating. On examination, you note some enlarged nontender lymph nodes in the posterior cervical chain, as well as a large supraclavicular node. Review of his growth chart shows a 12% weight loss from his annual visit only a few months ago. A chest x-ray shows an anterior mediastinal mass and hilar adenopathy. Which of the following is the most likely diagnosis?

A 10-year-old with Sickle Cell anemia is admitted to your fl…

A 10-year-old with Sickle Cell anemia is admitted to your floor with fever, cough, tachypnea and diminished breath sounds over both lower lobes. His CXR shows infiltrates and consolidation in both lower lobes and his lab work shows leukocytosis and a decreased hemoglobin. Treatment for this patient includes: