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A patient sample is mixed with 5M urea.  After 24 hours, the clot is not fully formed and the supernatant is markedly turbid.  What is the most likely interpretation of this result?

A patient has developed aspirin tolerance and the physician has started him on Plavix (Clopidogrel) because of a previous acute myocardial infarction (AMI).  How will his laboratory monitoring change?

A two year old boy was taken to the physician for severe eczema and epistaxis.  The boy has had a history of recurrent infections and cardiac problems.  Previously, he has been successfully treated with antibiotics for the eczema.  Upon physical examination, the physician noted several bruises on his left upper and right lower extremities along with patches of eczema and dermatitis.  The aunt mentioned that several men in their family had suffered from the same symptoms.  The physician ordered the following tests:   TEST RESULT REFERENCE RANGE WBC 6.0 x 10^3/ul 3.5-11.0 x 10^3/ul PLT 190 x 10^3/ul 150-400 x 10^3/ul PT 12.0 sec 11-13 sec APTT 28 sec 23-32 sec BT 17 min 2-10 min This disorder has a triad pathology. All of the following are included in the triad pathology except:

A lab report shows a thrombin time of 18 sec (RR: 10-15 sec) and a reptilase time of 15 sec (RR: 15-20 sec).  What can you conclude from this?

Lack of glycoprotein 1b/IX results in a defect in ____________

A prolonged aPTT and PT are corrected when mixed with normal pooled plasma.  Which of the following factors is most likely deficient?

Hemostasis is defined as:

An OB patient has just delivered a baby. Upon physical examination, the patient is febrile and pale.  The physician in charge of his care runs a battery of labs.  The results are below: TEST Patient results Reference Range Prothrombin Time 16.8 sec 11-13 sec INR 3.85 NA Activated Partial Thromboplastin Time 71 sec 23-32 sec Fibrinogen 75 mg/dl 200-400 mg/dl Factor X 22% >50% activity Factor II 21% >50% activity Factor VII 23% >50% activity Factor V 28% >50% activity Factor XII 25% >50% activity Factor VIII 28% >50% activity Factor XI 19% >50% activity Factor IX 30% >50% activity Protein C 5% >50% activity Protein S 8% >50% activity D-dimer 580 ng/ml

A prolonged aPTT is corrected with factor VIII-deficient plasma but not with factor IX-deficient plasma.  Which factor is deficient?

A patient has developed aspirin tolerance and the physician has started him on Plavix (Clopidogrel) because of a previous acute myocardial infarction (AMI).  How will his laboratory monitoring change?