Answer only one of the questions below, either 2 OR 3 (15 to…

Answer only one of the questions below, either 2 OR 3 (15 total points)   Question 2: Shyam Mohapatra  Briefly and temporally delineate and describe the phases of the humoral immune response beginning with antigen recognition and terminating with the generation of functional immunoglobulins of the IgG isotype. Include all appropriate cell types and interactions involved in your description. Assume that the antigen is a protein, which would elicit “help” from T helper cells. Be brief but as comprehensive as possible.   Question 3: Shyam Mohapatra  Describe the differences between thymus (i.e. T cell) dependent and thymus (i.e. T cell) independent immune responses, including examples of the antigens for T dependent and T independent responses and the nature of the antibody responses elicited by these 2 types of antigens. Be as brief but as comprehensive as possible.  

Answer only one of the questions below, either 4 OR 5 (15 to…

Answer only one of the questions below, either 4 OR 5 (15 total points)   Question 4: Shyam Mohapatra –  How do macrophages kill their prey?  Provide two examples of macrophage products that play a pivotal role in this process. “Intracellular microbes or parasites have evolved, however, methods to overcome the ‘wrath’ of macrophage and have developed survival mechanisms’. Justify this statement with one example.    Question 5: Shyam Mohapatra – “All roads lead to Rome”. How does this statement apply to innate immunity? Provide examples using responses to bacteria and viruses that utilize a specific set of pattern recognition receptors.