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ANTIFUNGALS … Antifungal drugs exploit the biochemical differences between healthy cells and infected cell. *** a) The “azole” class of antifungal drugs, function by inhibiting the production of what sterol that is unique to fungi? [blank1] *** b) What is the sterol found in normal mammalian cell membranes? [blank2] *** c) Consider the portion of the biosynthesis pathway for a key component of the fungal membrane … What type of enzyme is responsible for this reaction? [blank7] *** d) Name an antifungal “azole” drug discussed in class. [blank3] *** e) What metal element are these drugs attracted to in the active sites of fungal enzymes (hint: and also P450s)? [blank4] *** f)  Consider the portion of the biosynthesis pathway for a key component of the fungal membrane … What type of enzyme is responsible for this reaction?  [blank5] *** g) Would the reaction shown above be classified as a Phase I or Phase II type reaction? [blank6]

Pharmacist’s Guide to Herbals…

What is the calculation formula for C-Section Rate

Bonus Question:  Fill in the number of days for each month.  This is for a non-leap year.   Month Number of Days January February March April May June July August September October November December

From July through December, Community Hospital had 32 patients with complications and 2,394 discharges.  Calculate the complication rate.  Round to two decimal places. 

In February, Community Hospital had 289 discharges and deaths.  Twelve of these patients had HAIs.  Calculate the nonsocomial infection rate.  Round to two decimal places.  

What is the calculation formula for Bed Occupancy Rate?

What is the calculation formula for Rate

Calculate the LOS for the following discharged patients in an acute-care facility using the method listed.   Date admitted Date discharged LOS 7/9 7/9 9/12 9/22 3/10 3/24 6/17 7/18 10/20 11/25

The table that follows is a sample report for a hospital showing the discharges and deaths for the last quarter of the year.  Notice that this report lists the patient discharges and deaths by physicians on the medical staff.  Fill in the Gross Mortality Rate for each physician and give the total at the bottom.  Make sure to round to  the nearest hundredth of a percent and make sure to include a leading zero if applicable.  (Example of this is .34 should be entered in as 0.34.)  You do not need to include the % sign in with your answer. Physician number No of live discharges No of deaths Gross Mortality Rate Dr. 097 12 3 Dr. 123 204 4 Dr. 256 12 1 Dr. 372 92 4 Dr. 431 124 6 Dr. 537 79 2 Dr. 638 107 4 Dr. 725 85 3 Dr. 800 100 1 Dr. 901 158 8 Total 973 36