An alcoholic patient is admitted to hospital with signs of W…

An alcoholic patient is admitted to hospital with signs of Wernicke’s encephalopathy. They are prescribed Pabrinex® IV High Potency Injection at a dose of 10mL of Pabrinex® No 1 ampoule every eight hours for two days and 10mL of Pabrinex® No 2 ampoule every eight hours for two days. How many milligrams of thiamine hydrochloride will be administered to the patient over the first 24 hours of treatment?   Extract from the SPC for Pabrinex

JP’s generalized tonic-clonic seizures remain uncontrolled,…

JP’s generalized tonic-clonic seizures remain uncontrolled, despite being on maximally tolerated doses of carbamazepine, and his consultant neurologist has decided to switch him from carbamazepine to lamotrigine. Briefly describe and explain how JP’s neurologist would be expected to implement the switch from carbamazepine to lamotrigine (5 Marks)