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Mrs TR (weight 60 kg) is 56 years old with a history of smoking and COPD. She is admitted to the respiratory ward after an appointment with the GP. She is currently prescribed a salbutamol inhaler, beclomethasone / formoterol (Fostair) inhaler and theophylline (Slo-Phyllin) 500mg twice daily.    Calculate Mrs TR’s theophylline clearance in L/h.  Give your answer to TWO (2) decimal places.    CL Theo = 0.04 L/kg/h CL multiplication factors:  Smoking: 1.6 COPD: 0.8 

Compared to placebo, DRUG P reduces the rate of fatal cardiovascular events from 0.09 to 0.07. What is the number needed to treat?   ARC = the absolute risk of events in the control groupART = the absolute risk of events in the treatment groupARR (absolute risk reduction) = ARC – ARTNNT (number needed to treat) = 1 / ARR

You are a pharmacist working in a GP practice. You are undertaking a project to switch all suitable patients from Spiriva Handihaler® to Braltus Zonda®. Spiriva Handihaler® costs £34.87, whilst Braltus Zonda® costs £25.80. There are 78 patients prescribed Spiriva Handihaler®, and 74 patients are deemed suitable to be switched onto Braltus Zonda®. Assuming one inhaler is provided each month, what is the average monthly saving that is achieved by making this change? Give your answer in pounds to the nearest penny.

A dermatologist requests a 200 g preparation of hydrocortisone 2 % w/w. You only have a 2.5 % cream available and decide to dilute this with white soft paraffin. How many grams of the 2.5 % cream will be required for you to extemporaneously prepare the required 2 % w/w cream?  

You work in a hospice and see a patient with severe opioid responsive pain. Unfortunately, the patient has been unable to tolerate morphine and oxycodone due to persistent confusion and hallucinations. The palliative care consultant recommends a trial of oral hydromorphone. The patient is currently prescribed oxycodone 40 mg MR tablets at a dose of ONE tablet to be taken TWICE A DAY PO. Using the table below, what dose of hydromorphone would provide an equivalent daily dose? Give your answer in milligrams to the nearest whole number.   Extract from Online BNF

According to Archer, the mixtures of failures and successes in hotels on southwest 13th street in Gainesville reveals market ____________ in real estate.

A six-month-old child weighing 6.8 kg is prescribed treatment for acute pyelonephritis with oral co-amoxiclav 125 mg/31 mg/5 mL suspension at a dose of 0.25 mL/kg every 8 hours for 10 days. What is the total volume in millilitres of co-amoxiclav that should be prescribed for the full treatment duration? Give your answer in millilitres.

Important documents for a condominium owner to understand include all EXCEPT the:

Suppose a borrower defaults on two mortgage liens, a first mortgage of $150,000 and a second mortgage of $50,000, and the amount of money recovered from foreclosure is $100,000, how much money can the holder of the second mortgage expect to recover?

The idea of form-based zoning is to arrange land uses in a “city” by the user’s  _________________.