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List 3 barrier defenses of the vertebrate immune system.

Explain why both replication inhibitors and protease inhibitors must be used together in order to stop progression of HIV infections to AIDS.

What pathogen was targeted by the world’s first vaccine?  (HINT:  This pathogen no longer exists in the world today.)

Auer rods enhance the reaction of which cytochemical stain?

What is the main difference between the myeloperoxidase stain (MPX) and the sudan black B (SBB) stain? 

How are you supposed to contact your instructor? 

Where in your Canvas course will go to find all of the assignments and readings? 

Which signs and symptoms would lead the nurse to suspect hypoglycemia in the newborn?

Is the bolded statement TRUE or FALSE? Protein folding is an excellent study in changes within enthalpy, entropy, and free energy and the stabilization of a system in its final state. Given this subject classify the following as true or false.   46. Formation of disulfide bonds can lead to a greater Hbonds formed than Hbonds broken and a negative change in enthalpy for folding. 47. Formation of ionic bonds within the hydrophobic core can lead to a greater Hbonds formed than Hbonds broken and, as a result, a more stable protein (relative to a protein without these interactions). 48. Ionic bonds within the hydrophobic core are stronger than ionic bonds in water. 49. A globular protein typically will not fold in nonpolar environments as it will be entropically unfavorable to do so. 50. Mutation of a cysteine involved in a disulfide bond to serine will increase the protein’s Tm.  

Some Potentially Useful Information:  ∆G=∆H-T∆S V­0 = Vmax[S]/Km+ [S] Vmax = kcat[ET] Inversely proportional is a mathematically precise statement that is the opposite of directly proportional.  In inverse proportionality if a constant goes up than the constant that is “inversely proportional” to it will go down or vice-versa.