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You are studying a transcription factor that is regulated by phosphorylation of serine residues, which inactivates its nuclear localization signal. How would mutating these serines to alanines affect subcellular localization of the transcription factor and expression of its target gene(s)?

The fibrous proteins underlying the inner nuclear membrane are?

Which is not a role that lamins play in nuclear structure and function?

Binding of _______ to the regulatory subunits of protein kinase A induces conformation changes that cause dissociation of the catalytic subunits, in turn exposing _______ on the catalytic subunits.

Which process does not take place in the nucleus?

The outer nuclear membrane is contiguous with the?

snRNPs that are responsible for pre-mRNA splicing are assembled and stored in?

Azacytosine is an analog of cytosine with an N instead of a C in the 5 position of the pyrimidine ring. It cannot be methylated and, when incorporated into DNA, inhibits the activity of DNA methyltransferases. What effect would growing cells in the presence of azacytosine have on gene expression?

Which proteins can assemble in biomolecular condensates via liquid-liquid phase separation?

How does Ran determine the directionality of nuclear import?