A 33-year-old male with ulcerative colitis sees his physicia…

A 33-year-old male with ulcerative colitis sees his physician with complaints of itchy skin, fever, and right sided abdominal pain. Laboratory results on his blood sample indicate elevations in serum levels of both conjugated and unconjugated bilirubin, as well as elevated ALP. The client is sent for an ultrasound, which rules out gallstones. A subsequent blood tests returns positive with anti-mitochondrial antibodies. What is the most likely diagnosis for the client’s current state?

A nurse practitioner orders several laboratory tests on a 50…

A nurse practitioner orders several laboratory tests on a 50-year-old male client who is concerned about generalized pain, fatigue, and headaches. The serum test results return with elevated ALP, but γGT is within normal limits. Which pathophysiology is occurring in the client?