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The mechanism of action of warfarin involves: (1)1.      Inhibition of thrombin mediated platelet activation2.      Inhibition of the activation of plasminogen to plasmin3.      Inhibition of thromboxane A2 synthesis 4.      Inhibition of the synthesis of vitamin K-dependent clotting factors5.      Inhibiting platelet aggregation by binding to the P2Y12 receptor 

Losartan is associated with the following adverse effects: (1)1.       Vasoconstriction 2.       Hypertension 3.       Hyperglycemia4.       Hypokalemia5.       Dry cough

A 32-year-old man is diagnosed with whipworm disease after he spent the summer working outside without shoes on. The following is the best treatment option: (1)1.       Pyrantel pamoate2.       Mebendazole3.       Fluconazole4.      Praziquantel5.       Diethylcarbamazine 

Theophylline may be used in the following conditions: (1)1.    Chronic obstructive pulmonary disease2.    Malaria3.    Tuberculosis4.    African trypanosomiasis5.    Cutaneous leishmaniasis

A 48-year-old immigrant from Mexico presents with seizures and other neurologic symptoms. Eggs of Taenia solium are found in a stool specimen. A magnetic resonance image of the brain shows many cysts, some of which are calcified. The following drug would be of benefit to this individual: (1)1.    Ivermectin2.    Tranexamic acid3.    Albendazole4.    Diethylcarbamazine5.    Fluoxetine

The adverse effects of spironolactone include: (1)1.      Hypokalaemia2.      Excessive aldosterone secretion3.      Gynecomastia 4.      Peripheral oedema 5.      Hypernatraemia

The following drug prevents the intestinal absorption of cholesterol: (1)1.     Cholestyramine2.     Evolocumab3.   Ezetimibe4.   Bezafibrate5.   Eicosapentanoic acid

The following drug is used for control of tachycardia in a patient with hyperthyroidism: (1)1.   Digoxin2.   Propranolol3.   Levothyroxine sodium4.   Radioactive Iodine (I131)5.   Carbimazole

Warfarin is indicated for the treatment of the following: (1)1.   Intracranial bleeding2.   Hemorrhagic stroke 3.   Thromboembolism4.   Bleeding tendency5.   Thrombocytopaenia

The following medication is used to treat river blindness by targeting chloride channels and can cause a Mazzotti reaction: (1)1.      Ivermectin2.      Praziquantel3.      Metformin4.      Albendazole5.      Oseltamivir