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The following is the mechanism of action of mebendazole:                                          1.        It inhibits parasitic mitochondrial phosphorylation of adenosine diphosphate                                                                                                                                                   2.        It diminishes the energy production of the nematode                                                                                                                                                                                     3.        Causes death of parasites by increasing the permeability of the cell membrane to calcium ions                                                                                                                        4.        Enhances chloride influx leading to hyperpolarization, resulting in death of worm     5.        It is converted to hydrogen sulfide, which has a lethal action on the ectoparasite    

Doxazosin is indicated for:                                                                                                     1.        Erectile dysfunction2.        Benign prostatic hyperplasia3.        Stress urinary incontinence 4.        Urinary retention5.        Severe uncontrolled hypertension

The following drug is associated with psychiatric adverse effects of vivid dreams and       impaired concentration:                                                                                                                                                           1.                           Valacyclovir2.                           Tenofovir3.                           Zanamivir4.                           Ribavirin5.                           Efavirenz

HIV post exposure prophylaxis for occupational exposures may not be administered:                                                                                                                                                                              1.                           For exposures to fluids that contain blood2.                           If the source patient is HIV-seronegative, with features suggestive of a seroconversion illness3.                           If the healthcare worker is HIV-infected4.                           If the health care worker is not HIV-infected5.                           If the health care worker consents to HIV post-exposure prophylaxis

Severe skin irritation, burning and stinging is common while a patient is on treatment with the following drug:                                                                                                                  1.        Albendazole2.        Ivermectin3.        Niclosamide4.        Adrenaline5.        Benzyl benzoate

Match the following drugs with the relevant mechanism of action. Each drug may be used more than once or not at all:  

The following statement is true concerning HIV resistance to protease Inhibitors:    High-level resistance occurs to the reverse transcriptase enzyme.It occurs as an accumulation of stepwise mutations of the protease gene.It occurs to prevent allosteric inhibition of the reverse transcriptase enzyme.Resistance occurs as four specific substitutions of the integrase gene.A single-point mutation occurs within the integrase gene.

The following drug may be absorbed systemically, and patients should be warned  against possible disulfiram-like effects with concomitant alcohol consumption:       1.        Permethrin2.        Sulfiram3.        Benzyl benzoate4.        Niclosamide5.        Praziquantel

Match the following drugs with the relevant indications. Each drug may be used more than once or not at all:  

A newborn is being discharged to home.  The nurse is setting up a referral to see a Pulmonology specialist to rule out Cystic Fibrosis (CF).  What is the earliest recognizable clinical manifestation of CF?