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often interact through recognition domains like the SH2, SH3, and PH domains.

cause the tyrosine kinase to be constitutively active or “stuck on”.

always consist of multi-kinase “cascades”.

The following tables illustrate a loan of $1,750,000 with 5 annual payments of $415,444.  The loan started on 1/1/2013.  The first of 5 annual payments begain on 12/31/2013.  The loan carries an annual interest rate of  6%.  Using either table (each table has the same information/answers but is presented in two familiar formats) determine the amount of interest expense that would be allocated from the second annual payment.  The highlighted box is the answer students should provide for this question.

usually involve very stable intercellular signaling molecules.

is strongly affected by intermediate filament protein nucleotide binding (T-form & D-form).

all possess tyrosine kinase activity.

For questions 1 through 87, bubble in if the statement is true or false relative to their overarching statement (T or F). (55 points, 0.64 points each question)

signal response is dependent on how quickly the signal molecules are broken down.

Questions 19-22 Tyrosine kinase receptor mutations leading to cancer: