The following are true regarding bisphosphonates:           …

The following are true regarding bisphosphonates:                                                                                                      1.            Absorption after oral administration is poor.2.            They are the first-line treatment for only postmenopausal women with osteoporosis.3.            They are all dosed weekly.4.            They are safe to use in patients with severe renal impairment. 5.            They increase osteoclastic bone resorption.