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The following can increase half-life of a drug except: (1)1.        Diminished renal flow as result of a heart failure2.        Decreased extraction ratio as in renal disease3.        Decreased metabolism4.        Increased protein binding5.        Increased fat tissue in case of polar drugs.

A synthetic thyroxine sodium most commonly used is: (1)1.        Levothyroxine sodium2.        Carbimazole 3.        Potassium iodide solution4.        Radioactive iodine I131]5.        Liothyronine sodium

The following drug can be used for prevention of P. falciparum malaria during pregnancy: (1)1.        Atovaquone-proguanil2.        Metronidazole3.        Doxycycline4.        Mefloquine5.        Quinine

The following gastrointestinal agent cause discoloration of the tongue (black tongue): (1)1.        Amoxicillin2.        Lubiprostone3.        Sucralfate4.        Calcium carbonate5.        Bismuth subsalicylate

The following drug is indicated for both acute and chronic ulcerative colitis: (1)1.        Sulfasalazine2.        Prochlorperazine3.        Ciprofloxacin4.        Propantheline5.        Hyoscine butylbromide

Correct sequence of an administered drugs’movement through the body: (1)1.       Distribution – absorption – excretion– metabolism2.        Absorption – metabolism – excretion– distribution3.        Metabolism – absorption – distribution – excretion4.       Distribution – excretion– absorption – metabolism5.        Absorption – distribution – metabolism – excretion

The following suppress the cough center in the medulla: (1)1.        Guaifenesin2.        Bromhexine3.        Dextromethorphan4.        Salbutamol5.        Doxylamine

The following are receptor families except: (1)1.        Ligand-gated ion channels2.        G-Protein-coupled receptors3.        Enzyme linked receptors4.        Intracellular receptors5.        Free receptors

Enteral routes of drug administration include: (1)1.           Oral2.           Intramuscular3.           Intravenous4.           Topical 5.           Subcutaneous

The following combinations of drug and their mechanism of action is correct: (1)1.        Guaifenesin                           – stimulation of β2 receptor causing bronchodilation2.        Acetylcysteine                       – mast cell stabilization3.        Budesonide                           – leukotriene modulators4.        Theophylline                         – non-selective β2 receptor stimulation causing bronchodilation 5.        Xylometazoline                     – Vasoconstriction of the mucosal blood vessels, reducing oedema of the nasal mucosa