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Which of the following is an inflammatory cytokine that mediates proliferative signaling in the heart that also causes cardiac cachexia?

Which of the following correctly describes the consequence of a mutation in PDK4 (pyruvate dehydrogenase kinase 4)?

Inhibitors of the protein MLKL are being developed as potential therapies to inhibit which of the following forms of cell death?

Based on the Gompertzian kinetics curve below, which of the following would be the treatment of choice at point 3 for a solid tumor?

Most standard chemotherapy drugs inhibit DNA replication and therefore target which of the following cell cycle phases in cancer cells?

A Collie comes in with lymphoma and the MDR1 status of the dog is not known. Which of the following chemotherapeutics should you use to start treatment while awaiting the MDR1 test results?

Growth factors stimulate the cell cycle during which of the following phases?

Inhibitors of acetyl-CoA carboxylase are potential anti-cancer agents as they target which of the following metabolic changes in cancer cells?

Inhibition of the vascular endothelial growth factor (VEGF) receptor would have the highest impact on which of the following “Hallmarks of Cancer”?

The monoclonal antibody Bevacizumab prevents angiogenesis by binding which of the following growth factors?