You are caring for a 2yr old male in the PICU with necrotizi…

You are caring for a 2yr old male in the PICU with necrotizing Pneumonia. Patient is on maximal ventilator support, high dose epinephrine, and vasopressin and continues to have desaturation and difficulty ventilating. The team is considering ECMO, which of the following are contraindications to ECMO support?