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 How does the ionization of a drug impact its pharmacokinetics?

Which of the following statements is true concerning nutrition of articular cartilage?  

Which of the following is a sign of benzodiazepine withdrawal? 

What is the primary characteristic of orphan drugs?  

For a generic drug to establish Bioequivalence, all of the following must be met except which one? 

Calculate the bolus dose of Dantrolene in mg for a 350 pound patient. (Answer in a whole number)

A patient is given propofol and succinylcholine for induction of general anesthesia. After a multiple unsuccessful and difficult attempts at intubation, a glidescope arrives. It has been four minutes so repeated doses of propofol and succinylcholine are administered. What potential side effect may occur? 

In a hospital setting, some Parkinson patients may be on a monitored drug holiday. The goal of physical therapy during this scenario is: 

The idea of self-government is in the first three words of the Constitution. What are they?

Anti-seizure medications, such as Carbamazepine (Tegretol) and Divalproex sodium (Depakote) generally have which of the following mechanism of actions?