This lymphocytic disorder occurs primarily in males and pres…

This lymphocytic disorder occurs primarily in males and presents with massive splenomegaly and absent lymphadenopathy. Laboratory studies show pancytopenia and the occasional presence of abnormal lymphocytes with erratic cytoplasmic protrusions (shown below). Immunophenotypic studies reveal CD19, CD20, CD22, CD25, CD103, and CD11c.

When only a very few individuals give rise to a new populati…

When only a very few individuals give rise to a new population in a new area of favorable habitat, the new population might possess different genotype frequencies for a certain trait than the larger population from which it separated. This is called the _________ effect.