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The condition of eyes that do not look in the same direction…
The condition of eyes that do not look in the same direction at the same time is called strabismus.
Which markers are normally found on lymphoblasts?
Which markers are normally found on lymphoblasts?
A bone marrow sample is sent to the lab for cytochemical sta…
A bone marrow sample is sent to the lab for cytochemical staining. Results as follows: Myeloperoxidase: positive Sudan Black B: positive Non-specific Esterase: positiveBased on these findings, what lineage(s) is (are) most likely present?
A patient presents with acute leukemia with blasts identifie…
A patient presents with acute leukemia with blasts identified by a positive CD13, CD33, CD41, and CD61. The blasts stain positive with PAS, and NSE. Which translocation is commonly associated with this subtype of leukemia?
A 55-year-old male presents with fatigue, weight loss, and p…
A 55-year-old male presents with fatigue, weight loss, and pruritus. Laboratory studies reveal leukocytosis, elevated basophils with immature forms on a peripheral smear, >20% basophilic blasts in the bone marrow, and elevated serum histamine levels. What best explains the relationship between hyperhistaminemia and the patient’s condition?
A 45-year-old female was evaluated by her physician because…
A 45-year-old female was evaluated by her physician because she had unexplained bruising on her upper torso. Patient history was unremarkable. Physical examination revealed a palpable liver and spleen. CBCo WBC count: 72 × 109/Lo Hb: 8.7 g/dL o Hct: 25% o Normal indices o PLT count: 55 × 109/L Differential: 40% blasts, 30% promyelocytes, 10% myelocytes, 4% metamyelocytes, 5% bands, 11% segemented neutrophils Cytogenetics have been ordered – what abnormality is likely to be detected?
The WHO generally defines acute lymphoblastic leukemia as ha…
The WHO generally defines acute lymphoblastic leukemia as having a blast count that is which of the following?
A patient presents with a morphological smear examination re…
A patient presents with a morphological smear examination revealing >20% blasts with prominent granules and Auer rods. A 25% monocyte count was seen in the peripheral smear. There were no recurrent cytogenetic abnormalities observed. Under which classification of acute leukemia, not otherwise specific, does this diagnosis fall?
An adult patient presents with 44% blasts. The blasts are mo…
An adult patient presents with 44% blasts. The blasts are monomorphic, with abundant basophilic cytoplasm. The majority of blasts show prominent vacuolization (shown below). Cytogenetics shows translocation of the MYC gene (8q24) to the IgH chain locus [t(8;14)]. What is the diagnosis?