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The use of cAMP as a second messenger in signal transduction…

The use of cAMP as a second messenger in signal transduction is common in many cells. Generally, the process of signal transduction using heterotrimeric G-proteins can be described as an eight-step process.  Choose the correct statements and bring the steps into the correct order from beginning to last! BE CAREFUL, not all statements are needed, you have to read carefully! 1) Gα(GTP) binds to adenylate cyclase and activates the enzyme 2) Gβγ(GTP) binds to adenylate cyclase and activates the enzyme 3) The intrinsic hydrolase activity of Gα converts GTP to GDP, Gα(GDP)is formed 4) The intrinsic hydrolase activity of Gβγ converts GTP to GDP, Gβγ(GDP)is formed 5) Binding of the hormone to the G protein-coupled receptor (GPCR) 6) Gα(GDP) and Gβγ reform the initial heterotrimeric G protein and the cycle can begin again 7) Gβγ(GDP) and Gα reform the initial heterotrimeric G protein and the cycle can begin again 8) The heterotrimeric G protein falls apart into Gα(GTP) and Gβγ 9) The heterotrimeric G protein falls apart into Gα and Gβγ(GTP) 10) Adenylate cyclase catalyzes the synthesis of cAMP from ATP 11) Adenylate cyclase catalyzes the synthesis of cAMP from AMP 12) The heterotrimeric G protein is activated and the Gα subunit exchanges its bound GDP for GTP 13) The heterotrimeric G protein is activated and the Gβγ subunit exchanges its bound GDP for GTP 14) Gα(GDP) dissociates from adenylate cyclase, which deactivates the enzyme 15) Gβγ(GDP) dissociates from adenylate cyclase, which deactivates the enzyme