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The following statement is true concerning viral resistance to HIV protease inhibitors:                                                                                                                                                                             1.        High-level resistance occurs to the reverse transcriptase enzyme.2.        It occurs as an accumulation of stepwise mutations of the protease gene.3.       It occurs to prevent allosteric inhibition of the reverse transcriptase enzyme.4.        Resistance occurs as four specific substitutions of the integrase gene.5.       A single-point mutation occurs within the integrase gene.

The following benzodiazepine is not used in anaesthesia:                                    1.        Midazolam2.        Loprazolam3.        Lorazepam4.        Diazepam5.        Alprazolam

The following statements is correct regarding tachyphylaxis:                                        1.       There is a decreased receptor-mediated response to a drug 2.       There is an increased risk of side effects occurring3.       Smaller doses cause an increased response to a drug4.       The rate of drug infusion equals the rate of excretion5.       The drug does not bind to receptors completely

Amoebiasis therapy includes the following:                                                                        1.        Tenofovir2.        Niacin3.        Metronidazole4.        Isoniazid5.        Lamivudine

The following are contra-indications for ketamine except                                                1.        Hypertension2.        Sepsis3.        Cardiac failure4.        Myocardial infarction5.        Increased intraocular pressure 

The following drug may be used to facilitate endotracheal intubation: 1.        Metformin2.        Diclofenac3.        Carbocisteine4.        Tramadol5.        Atracurium   

 12.    The following can be administered orally:                                                                              1.        Benzylpenicillin2.        Procaine benzylpenicillin3.       Benzathine benzylpenicillin4.        Phenoxymethylpenicillin5.        Methicillin

The following reaction represents phase II of drug metabolism:                                    1.       Amidation2.       Hydrolysis 3.       Oxidation4.       Reduction5.       Sulfation

The following is classified as β-lactam antimicrobial agents:                              1.       Glycopeptides2.       Lincosamides3.       Macrolides4.        Aminoglycosides5.        Cephalosporins

Step 1 management of mild pain includes the following:                                                   1.        Amitriptyline2.        Morphine3.        Tramadol4.        Ketamine5.        Ibuprofen